Q/A & Q/C Practical Training Programme

• What is Quality? What is Quality Assurance (Q/A)? What is Quality Control (Q/C)?
• Q/A vs. Q/C — scope, responsibility and overlap
• Quality Management System — basic concept
• Role of Q/A in industry; responsibilities of the Q/C Chemist
• Industrial laboratory workflow and quality culture
• Quality specifications and acceptance criteria
• Importance of analytical testing; common quality failures

Part A — Sampling

• Importance of representative sampling
• Sampling techniques
• Sample identification and labeling
• Sample storage and contamination control
• Sample preparation and dilution
• Weighing and measurement considerations

Part B — Laboratory Documentation

• Standard Operating Procedure (SOP) and test method vs. specification
• Laboratory Worksheet and raw-data recording
• Test Request Form and batch/lot number
• Certificate of Analysis (COA)
• OOS – Out of Specification; OOT – Out of Trend
• CAPA – Corrective and Preventive Action

Practical 1 — pH Measurement

• pH meter components and calibration concept
• Buffer solution preparation and use
• Sample preparation and measurement procedure
• Result recording and common sources of error

Practical 2 — Analytical Balance & Solution Preparation

• Proper balance operation and the tare function
• Correct weighing technique for accurate measurement
• Preparation of a standard/sample solution
• Proper labeling of prepared solutions

Practical 3 — Dilution Technique

• Stock solution vs. working solution
• Dilution factor and volumetric flask usage
• Pipetting technique
• Basic dilution calculation using C₁V₁ = C₂V₂ — participants solve a practical dilution problem

• Burette preparation and pipette use
• Indicator selection
• Titration procedure and endpoint detection
• Concordant readings
• Calculation of concentration/assay

Instrument Overview

• UV-Visible Spectrophotometer
• HPLC (High-Performance Liquid Chromatography)
• GC (Gas Chromatography)
• FTIR (Fourier-Transform Infrared Spectroscopy)
• Digital pH Meter
• Conductivity Meter
• Analytical Balance

Key Concepts

• Working principle and instrument components
• Calibration; blank, standard and sample measurement
• System suitability — introductory concept
• Basic troubleshooting and instrument maintenance

Live Demonstration — UV-Visible Spectrophotometer

• Instrument startup and component walkthrough
• Blank preparation
• Standard/sample preparation and cuvette handling
• Absorbance measurement
• Result recording and basic interpretation

• Test result vs. specification; acceptance criteria; Pass/Fail decision
• Accuracy, precision, repeatability, reproducibility
• Mean/average, standard deviation and %RSD
• Analytical error, calibration error, and measurement uncertainty — introductory concept

Problem → Root Cause → Corrective Action → Preventive Action → Verification

• 10–15 Multiple Choice Questions (MCQs)
• Short Q&A
• Basic Q/C calculation
• Practical observation
• Mini case-study question